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Engineered TALE Repeats for Enhanced Imaging‐Based Analysis of Cellular 5‐Methylcytosine

Transcription‐activator‐like effectors (TALEs) are repeat‐based, programmable DNA‐binding proteins that can be engineered to recognize sequences of canonical and epigenetically modified nucleobases. Fluorescent TALEs can be used for the imaging‐based analysis of cellular 5‐methylcytosine (5 mC) in r...

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Detalles Bibliográficos
Autores principales: Muñoz‐López, Álvaro, Jung, Anne, Buchmuller, Benjamin, Wolffgramm, Jan, Maurer, Sara, Witte, Anna, Summerer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894354/
https://www.ncbi.nlm.nih.gov/pubmed/32991020
http://dx.doi.org/10.1002/cbic.202000563