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Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894379/ https://www.ncbi.nlm.nih.gov/pubmed/33628677 http://dx.doi.org/10.7759/cureus.12809 |
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author | Natarajan, Jyotsna M Born, Donald E Harsh, Griffith Shuer, Lawrence M Soltys, Scott G |
author_facet | Natarajan, Jyotsna M Born, Donald E Harsh, Griffith Shuer, Lawrence M Soltys, Scott G |
author_sort | Natarajan, Jyotsna M |
collection | PubMed |
description | For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted, as it may be curable. We present a patient with multiply recurrent intracranial meningiomas over 19 years, with a transformation from grade I to grade II histology, with oligometastatic disease to the C5 vertebral body. Three years following definitive spinal stereotactic radiosurgery, she remains without evidence of other metastatic diseases. Our case highlights the oncologic concept that metastatic meningioma need not be widely disseminated and provides the clinical rationale for aggressive local treatment of an oligometastatic meningioma. |
format | Online Article Text |
id | pubmed-7894379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-78943792021-02-23 Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine Natarajan, Jyotsna M Born, Donald E Harsh, Griffith Shuer, Lawrence M Soltys, Scott G Cureus Radiation Oncology For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted, as it may be curable. We present a patient with multiply recurrent intracranial meningiomas over 19 years, with a transformation from grade I to grade II histology, with oligometastatic disease to the C5 vertebral body. Three years following definitive spinal stereotactic radiosurgery, she remains without evidence of other metastatic diseases. Our case highlights the oncologic concept that metastatic meningioma need not be widely disseminated and provides the clinical rationale for aggressive local treatment of an oligometastatic meningioma. Cureus 2021-01-20 /pmc/articles/PMC7894379/ /pubmed/33628677 http://dx.doi.org/10.7759/cureus.12809 Text en Copyright © 2021, Natarajan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiation Oncology Natarajan, Jyotsna M Born, Donald E Harsh, Griffith Shuer, Lawrence M Soltys, Scott G Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title | Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title_full | Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title_fullStr | Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title_full_unstemmed | Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title_short | Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine |
title_sort | intracranial grade ii meningioma oligometastatic to the cervical spine |
topic | Radiation Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894379/ https://www.ncbi.nlm.nih.gov/pubmed/33628677 http://dx.doi.org/10.7759/cureus.12809 |
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