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Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine

For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted...

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Autores principales: Natarajan, Jyotsna M, Born, Donald E, Harsh, Griffith, Shuer, Lawrence M, Soltys, Scott G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894379/
https://www.ncbi.nlm.nih.gov/pubmed/33628677
http://dx.doi.org/10.7759/cureus.12809
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author Natarajan, Jyotsna M
Born, Donald E
Harsh, Griffith
Shuer, Lawrence M
Soltys, Scott G
author_facet Natarajan, Jyotsna M
Born, Donald E
Harsh, Griffith
Shuer, Lawrence M
Soltys, Scott G
author_sort Natarajan, Jyotsna M
collection PubMed
description For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted, as it may be curable. We present a patient with multiply recurrent intracranial meningiomas over 19 years, with a transformation from grade I to grade II histology, with oligometastatic disease to the C5 vertebral body. Three years following definitive spinal stereotactic radiosurgery, she remains without evidence of other metastatic diseases. Our case highlights the oncologic concept that metastatic meningioma need not be widely disseminated and provides the clinical rationale for aggressive local treatment of an oligometastatic meningioma.
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spelling pubmed-78943792021-02-23 Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine Natarajan, Jyotsna M Born, Donald E Harsh, Griffith Shuer, Lawrence M Soltys, Scott G Cureus Radiation Oncology For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted, as it may be curable. We present a patient with multiply recurrent intracranial meningiomas over 19 years, with a transformation from grade I to grade II histology, with oligometastatic disease to the C5 vertebral body. Three years following definitive spinal stereotactic radiosurgery, she remains without evidence of other metastatic diseases. Our case highlights the oncologic concept that metastatic meningioma need not be widely disseminated and provides the clinical rationale for aggressive local treatment of an oligometastatic meningioma. Cureus 2021-01-20 /pmc/articles/PMC7894379/ /pubmed/33628677 http://dx.doi.org/10.7759/cureus.12809 Text en Copyright © 2021, Natarajan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Natarajan, Jyotsna M
Born, Donald E
Harsh, Griffith
Shuer, Lawrence M
Soltys, Scott G
Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title_full Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title_fullStr Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title_full_unstemmed Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title_short Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine
title_sort intracranial grade ii meningioma oligometastatic to the cervical spine
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894379/
https://www.ncbi.nlm.nih.gov/pubmed/33628677
http://dx.doi.org/10.7759/cureus.12809
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