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Clinical features of patients undergoing hemodialysis with COVID‐19

Hemodialysis patients are susceptible to coronavirus disease 2019 (COVID‐19). The aim of this study was to describe the epidemiological, clinical characteristics, and mortality‐related risk factors for those who undergoing hemodialysis with COVID‐19. We conducted a retrospective study. A total of 49...

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Autores principales: Tian, Ming, Li, Hua, Yan, Ting, Dai, Yujie, Dong, Liping, Wei, Honglan, Song, Xiaohong, Dong, Junwu, Cheng, Fangxiong, Li, Wenzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894471/
https://www.ncbi.nlm.nih.gov/pubmed/33118200
http://dx.doi.org/10.1111/sdi.12928
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author Tian, Ming
Li, Hua
Yan, Ting
Dai, Yujie
Dong, Liping
Wei, Honglan
Song, Xiaohong
Dong, Junwu
Cheng, Fangxiong
Li, Wenzhou
author_facet Tian, Ming
Li, Hua
Yan, Ting
Dai, Yujie
Dong, Liping
Wei, Honglan
Song, Xiaohong
Dong, Junwu
Cheng, Fangxiong
Li, Wenzhou
author_sort Tian, Ming
collection PubMed
description Hemodialysis patients are susceptible to coronavirus disease 2019 (COVID‐19). The aim of this study was to describe the epidemiological, clinical characteristics, and mortality‐related risk factors for those who undergoing hemodialysis with COVID‐19. We conducted a retrospective study. A total of 49 hemodialysis patients with COVID‐19 (Group 1) and 74 uninfected patients (Group 2) were included. For patients in Group 1, we found the median age was 62 years (36‐89 years), 59.3% were male, and the median dialysis vintage was 26 months. Twenty‐eight patients (57%) had three or more comorbidities and two patients (4%) died. The most common symptoms were fever (32.7%) and dry cough (46.9%), while nine patients (18.4%) were asymptomatic. Blood routine tests indicated lymphocytopenia, the proportion of lymphocyte subsets was generally reduced, and chest CT scans showed ground‐glass opacity (45.8%) and patchy shadowing (35.4%). However, these findings were not specific to hemodialysis patients with COVID‐19, and similar manifestations could be found in patients without SARS‐CoV‐2 infection. In conclusion, for hemodialysis patients with COVID‐19, lymphocytopenia and ground‐glass opacities or patchy opacities were common but not specific to them, early active treatment and interventions against nosocomial infection can significantly reduce the mortality and the risk of SARS‐CoV‐2 infection.
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spelling pubmed-78944712021-03-02 Clinical features of patients undergoing hemodialysis with COVID‐19 Tian, Ming Li, Hua Yan, Ting Dai, Yujie Dong, Liping Wei, Honglan Song, Xiaohong Dong, Junwu Cheng, Fangxiong Li, Wenzhou Semin Dial Original Articles Hemodialysis patients are susceptible to coronavirus disease 2019 (COVID‐19). The aim of this study was to describe the epidemiological, clinical characteristics, and mortality‐related risk factors for those who undergoing hemodialysis with COVID‐19. We conducted a retrospective study. A total of 49 hemodialysis patients with COVID‐19 (Group 1) and 74 uninfected patients (Group 2) were included. For patients in Group 1, we found the median age was 62 years (36‐89 years), 59.3% were male, and the median dialysis vintage was 26 months. Twenty‐eight patients (57%) had three or more comorbidities and two patients (4%) died. The most common symptoms were fever (32.7%) and dry cough (46.9%), while nine patients (18.4%) were asymptomatic. Blood routine tests indicated lymphocytopenia, the proportion of lymphocyte subsets was generally reduced, and chest CT scans showed ground‐glass opacity (45.8%) and patchy shadowing (35.4%). However, these findings were not specific to hemodialysis patients with COVID‐19, and similar manifestations could be found in patients without SARS‐CoV‐2 infection. In conclusion, for hemodialysis patients with COVID‐19, lymphocytopenia and ground‐glass opacities or patchy opacities were common but not specific to them, early active treatment and interventions against nosocomial infection can significantly reduce the mortality and the risk of SARS‐CoV‐2 infection. John Wiley and Sons Inc. 2020-10-29 2021 /pmc/articles/PMC7894471/ /pubmed/33118200 http://dx.doi.org/10.1111/sdi.12928 Text en © 2020 The Authors. Seminars in Dialysis published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Tian, Ming
Li, Hua
Yan, Ting
Dai, Yujie
Dong, Liping
Wei, Honglan
Song, Xiaohong
Dong, Junwu
Cheng, Fangxiong
Li, Wenzhou
Clinical features of patients undergoing hemodialysis with COVID‐19
title Clinical features of patients undergoing hemodialysis with COVID‐19
title_full Clinical features of patients undergoing hemodialysis with COVID‐19
title_fullStr Clinical features of patients undergoing hemodialysis with COVID‐19
title_full_unstemmed Clinical features of patients undergoing hemodialysis with COVID‐19
title_short Clinical features of patients undergoing hemodialysis with COVID‐19
title_sort clinical features of patients undergoing hemodialysis with covid‐19
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894471/
https://www.ncbi.nlm.nih.gov/pubmed/33118200
http://dx.doi.org/10.1111/sdi.12928
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