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Poly(ADP‐ribose) glycohydrolase silencing‐mediated H2B expression inhibits benzo(a)pyrene‐induced carcinogenesis

Poly(ADP‐ribose) glycohydrolase (PARG) as a main enzyme hydrolyzing poly(ADP‐ribose) in eukaryotes, and its silencing can inhibit benzo(a)pyrene (BaP)‐induced carcinogenesis. A thorough understanding of the mechanism of PARG silenced inhibition of BaP‐induced carcinogenesis provides a new therapeuti...

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Detalles Bibliográficos
Autores principales: Zeng, Zhuoying, Lu, Jingjing, Wu, Desheng, Zuo, Ran, Li, Yuxi, Huang, Haiyan, Yuan, Jianhui, Hu, Zhangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894510/
https://www.ncbi.nlm.nih.gov/pubmed/33044785
http://dx.doi.org/10.1002/tox.23034