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Poly(ADP‐ribose) glycohydrolase silencing‐mediated H2B expression inhibits benzo(a)pyrene‐induced carcinogenesis
Poly(ADP‐ribose) glycohydrolase (PARG) as a main enzyme hydrolyzing poly(ADP‐ribose) in eukaryotes, and its silencing can inhibit benzo(a)pyrene (BaP)‐induced carcinogenesis. A thorough understanding of the mechanism of PARG silenced inhibition of BaP‐induced carcinogenesis provides a new therapeuti...
Autores principales: | Zeng, Zhuoying, Lu, Jingjing, Wu, Desheng, Zuo, Ran, Li, Yuxi, Huang, Haiyan, Yuan, Jianhui, Hu, Zhangli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894510/ https://www.ncbi.nlm.nih.gov/pubmed/33044785 http://dx.doi.org/10.1002/tox.23034 |
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