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Resolving the Molecular Steps in Clostridial Neurotoxin Light Chain Translocation
The clostridial neurotoxins (CNTs), botulinum toxin and tetanus toxin, are the most toxic proteins for humans. Neurotoxicity is based upon the specificity of the CNTs for neural host receptors and substrates. CNTs are organized into three domains, a Light Chain (LC) that is a metalloprotease and a H...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894615/ https://www.ncbi.nlm.nih.gov/pubmed/33615314 http://dx.doi.org/10.33696/Neurol.1.020 |