Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells

OBJECTIVE(S): Cystic fibrosis (CF) is an inherited autosomal recessive disease that is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The present study aimed to investigate the genetic modification of CF with ΔF508 mutation of the CFTR gene using CRISPR i...

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Detalles Bibliográficos
Autores principales: Khatibi, Sepideh, Modaresi, Mohammadreza, Kazemi Oskuee, Reza, Salehi, Mohammad, Aghaee-Bakhtiari, Seyed Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894636/
https://www.ncbi.nlm.nih.gov/pubmed/33643573
http://dx.doi.org/10.22038/ijbms.2020.50051.11415

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