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Uncovering New Challenges in Targeting Glycolysis to Treat Th17 Cell-Mediated Autoimmunity
Targeting glycolysis in T helper 17 (Th17) cells presents an attractive opportunity to treat Th17 cell-mediated autoimmune diseases such as multiple sclerosis (MS). Pyruvate kinase isoform 2 (PKM2) is a glycolytic enzyme expressed in T cells infiltrating the central nervous system in a mouse model o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894650/ https://www.ncbi.nlm.nih.gov/pubmed/33614166 http://dx.doi.org/10.20900/immunometab20210006 |