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Identifying Differentially Expressed Genes of Zero Inflated Single Cell RNA Sequencing Data Using Mixed Model Score Tests

Single cell RNA sequencing (scRNA-seq) allows quantitative measurement and comparison of gene expression at the resolution of single cells. Ignoring the batch effects and zero inflation of scRNA-seq data, many proposed differentially expressed (DE) methods might generate bias. We propose a method, s...

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Detalles Bibliográficos
Autores principales:	He, Zhiqiang, Pan, Yueyun, Shao, Fang, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894898/ https://www.ncbi.nlm.nih.gov/pubmed/33613638 http://dx.doi.org/10.3389/fgene.2021.616686

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