Cargando…

Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry

AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Díez-Manglano, Jesús, Solís-Marquínez, Marta Nataya, Álvarez García, Andrea, Alcalá-Rivera, Nicolás, Maderuelo Riesco, Irene, Gericó Aseguinolaza, Martín, Beato Pérez, José Luis, Méndez Bailón, Manuel, Labirua-Iturburu Ruiz, Ane-Elbire, García Gómez, Miriam, Martínez Cilleros, Carmen, Pesqueira Fontan, Paula María, Abella Vázquez, Lucy, Blázquez Encinar, Julio César, Boixeda, Ramon, Gil Sánchez, Ricardo, de la Peña Fernández, Andrés, Loureiro Amigo, José, Escobar Sevilla, Joaquín, Guzmán Garcia, Marcos, Martín Escalante, María Dolores, Magallanes Gamboa, Jeffrey Oskar, Martínez González, Ángel Luis, Lumbreras Bermejo, Carlos, Antón Santos, Juan Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894924/
https://www.ncbi.nlm.nih.gov/pubmed/33606820
http://dx.doi.org/10.1371/journal.pone.0247422
_version_ 1783653328956162048
author Díez-Manglano, Jesús
Solís-Marquínez, Marta Nataya
Álvarez García, Andrea
Alcalá-Rivera, Nicolás
Maderuelo Riesco, Irene
Gericó Aseguinolaza, Martín
Beato Pérez, José Luis
Méndez Bailón, Manuel
Labirua-Iturburu Ruiz, Ane-Elbire
García Gómez, Miriam
Martínez Cilleros, Carmen
Pesqueira Fontan, Paula María
Abella Vázquez, Lucy
Blázquez Encinar, Julio César
Boixeda, Ramon
Gil Sánchez, Ricardo
de la Peña Fernández, Andrés
Loureiro Amigo, José
Escobar Sevilla, Joaquín
Guzmán Garcia, Marcos
Martín Escalante, María Dolores
Magallanes Gamboa, Jeffrey Oskar
Martínez González, Ángel Luis
Lumbreras Bermejo, Carlos
Antón Santos, Juan Miguel
author_facet Díez-Manglano, Jesús
Solís-Marquínez, Marta Nataya
Álvarez García, Andrea
Alcalá-Rivera, Nicolás
Maderuelo Riesco, Irene
Gericó Aseguinolaza, Martín
Beato Pérez, José Luis
Méndez Bailón, Manuel
Labirua-Iturburu Ruiz, Ane-Elbire
García Gómez, Miriam
Martínez Cilleros, Carmen
Pesqueira Fontan, Paula María
Abella Vázquez, Lucy
Blázquez Encinar, Julio César
Boixeda, Ramon
Gil Sánchez, Ricardo
de la Peña Fernández, Andrés
Loureiro Amigo, José
Escobar Sevilla, Joaquín
Guzmán Garcia, Marcos
Martín Escalante, María Dolores
Magallanes Gamboa, Jeffrey Oskar
Martínez González, Ángel Luis
Lumbreras Bermejo, Carlos
Antón Santos, Juan Miguel
author_sort Díez-Manglano, Jesús
collection PubMed
description AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20–65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. RESULTS: As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067–0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). CONCLUSIONS: Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality.
format Online
Article
Text
id pubmed-7894924
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-78949242021-03-01 Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry Díez-Manglano, Jesús Solís-Marquínez, Marta Nataya Álvarez García, Andrea Alcalá-Rivera, Nicolás Maderuelo Riesco, Irene Gericó Aseguinolaza, Martín Beato Pérez, José Luis Méndez Bailón, Manuel Labirua-Iturburu Ruiz, Ane-Elbire García Gómez, Miriam Martínez Cilleros, Carmen Pesqueira Fontan, Paula María Abella Vázquez, Lucy Blázquez Encinar, Julio César Boixeda, Ramon Gil Sánchez, Ricardo de la Peña Fernández, Andrés Loureiro Amigo, José Escobar Sevilla, Joaquín Guzmán Garcia, Marcos Martín Escalante, María Dolores Magallanes Gamboa, Jeffrey Oskar Martínez González, Ángel Luis Lumbreras Bermejo, Carlos Antón Santos, Juan Miguel PLoS One Research Article AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20–65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. RESULTS: As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067–0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). CONCLUSIONS: Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality. Public Library of Science 2021-02-19 /pmc/articles/PMC7894924/ /pubmed/33606820 http://dx.doi.org/10.1371/journal.pone.0247422 Text en © 2021 Díez-Manglano et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Díez-Manglano, Jesús
Solís-Marquínez, Marta Nataya
Álvarez García, Andrea
Alcalá-Rivera, Nicolás
Maderuelo Riesco, Irene
Gericó Aseguinolaza, Martín
Beato Pérez, José Luis
Méndez Bailón, Manuel
Labirua-Iturburu Ruiz, Ane-Elbire
García Gómez, Miriam
Martínez Cilleros, Carmen
Pesqueira Fontan, Paula María
Abella Vázquez, Lucy
Blázquez Encinar, Julio César
Boixeda, Ramon
Gil Sánchez, Ricardo
de la Peña Fernández, Andrés
Loureiro Amigo, José
Escobar Sevilla, Joaquín
Guzmán Garcia, Marcos
Martín Escalante, María Dolores
Magallanes Gamboa, Jeffrey Oskar
Martínez González, Ángel Luis
Lumbreras Bermejo, Carlos
Antón Santos, Juan Miguel
Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title_full Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title_fullStr Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title_full_unstemmed Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title_short Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
title_sort healthcare workers hospitalized due to covid-19 have no higher risk of death than general population. data from the spanish semi-covid-19 registry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894924/
https://www.ncbi.nlm.nih.gov/pubmed/33606820
http://dx.doi.org/10.1371/journal.pone.0247422
work_keys_str_mv AT diezmanglanojesus healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT solismarquinezmartanataya healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT alvarezgarciaandrea healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT alcalariveranicolas healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT maderueloriescoirene healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT gericoaseguinolazamartin healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT beatoperezjoseluis healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT mendezbailonmanuel healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT labiruaiturbururuizaneelbire healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT garciagomezmiriam healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT martinezcilleroscarmen healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT pesqueirafontanpaulamaria healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT abellavazquezlucy healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT blazquezencinarjuliocesar healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT boixedaramon healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT gilsanchezricardo healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT delapenafernandezandres healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT loureiroamigojose healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT escobarsevillajoaquin healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT guzmangarciamarcos healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT martinescalantemariadolores healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT magallanesgamboajeffreyoskar healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT martinezgonzalezangelluis healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT lumbrerasbermejocarlos healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT antonsantosjuanmiguel healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry
AT healthcareworkershospitalizedduetocovid19havenohigherriskofdeaththangeneralpopulationdatafromthespanishsemicovid19registry