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Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894924/ https://www.ncbi.nlm.nih.gov/pubmed/33606820 http://dx.doi.org/10.1371/journal.pone.0247422 |
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author | Díez-Manglano, Jesús Solís-Marquínez, Marta Nataya Álvarez García, Andrea Alcalá-Rivera, Nicolás Maderuelo Riesco, Irene Gericó Aseguinolaza, Martín Beato Pérez, José Luis Méndez Bailón, Manuel Labirua-Iturburu Ruiz, Ane-Elbire García Gómez, Miriam Martínez Cilleros, Carmen Pesqueira Fontan, Paula María Abella Vázquez, Lucy Blázquez Encinar, Julio César Boixeda, Ramon Gil Sánchez, Ricardo de la Peña Fernández, Andrés Loureiro Amigo, José Escobar Sevilla, Joaquín Guzmán Garcia, Marcos Martín Escalante, María Dolores Magallanes Gamboa, Jeffrey Oskar Martínez González, Ángel Luis Lumbreras Bermejo, Carlos Antón Santos, Juan Miguel |
author_facet | Díez-Manglano, Jesús Solís-Marquínez, Marta Nataya Álvarez García, Andrea Alcalá-Rivera, Nicolás Maderuelo Riesco, Irene Gericó Aseguinolaza, Martín Beato Pérez, José Luis Méndez Bailón, Manuel Labirua-Iturburu Ruiz, Ane-Elbire García Gómez, Miriam Martínez Cilleros, Carmen Pesqueira Fontan, Paula María Abella Vázquez, Lucy Blázquez Encinar, Julio César Boixeda, Ramon Gil Sánchez, Ricardo de la Peña Fernández, Andrés Loureiro Amigo, José Escobar Sevilla, Joaquín Guzmán Garcia, Marcos Martín Escalante, María Dolores Magallanes Gamboa, Jeffrey Oskar Martínez González, Ángel Luis Lumbreras Bermejo, Carlos Antón Santos, Juan Miguel |
author_sort | Díez-Manglano, Jesús |
collection | PubMed |
description | AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20–65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. RESULTS: As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067–0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). CONCLUSIONS: Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality. |
format | Online Article Text |
id | pubmed-7894924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-78949242021-03-01 Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry Díez-Manglano, Jesús Solís-Marquínez, Marta Nataya Álvarez García, Andrea Alcalá-Rivera, Nicolás Maderuelo Riesco, Irene Gericó Aseguinolaza, Martín Beato Pérez, José Luis Méndez Bailón, Manuel Labirua-Iturburu Ruiz, Ane-Elbire García Gómez, Miriam Martínez Cilleros, Carmen Pesqueira Fontan, Paula María Abella Vázquez, Lucy Blázquez Encinar, Julio César Boixeda, Ramon Gil Sánchez, Ricardo de la Peña Fernández, Andrés Loureiro Amigo, José Escobar Sevilla, Joaquín Guzmán Garcia, Marcos Martín Escalante, María Dolores Magallanes Gamboa, Jeffrey Oskar Martínez González, Ángel Luis Lumbreras Bermejo, Carlos Antón Santos, Juan Miguel PLoS One Research Article AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20–65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. RESULTS: As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067–0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). CONCLUSIONS: Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality. Public Library of Science 2021-02-19 /pmc/articles/PMC7894924/ /pubmed/33606820 http://dx.doi.org/10.1371/journal.pone.0247422 Text en © 2021 Díez-Manglano et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Díez-Manglano, Jesús Solís-Marquínez, Marta Nataya Álvarez García, Andrea Alcalá-Rivera, Nicolás Maderuelo Riesco, Irene Gericó Aseguinolaza, Martín Beato Pérez, José Luis Méndez Bailón, Manuel Labirua-Iturburu Ruiz, Ane-Elbire García Gómez, Miriam Martínez Cilleros, Carmen Pesqueira Fontan, Paula María Abella Vázquez, Lucy Blázquez Encinar, Julio César Boixeda, Ramon Gil Sánchez, Ricardo de la Peña Fernández, Andrés Loureiro Amigo, José Escobar Sevilla, Joaquín Guzmán Garcia, Marcos Martín Escalante, María Dolores Magallanes Gamboa, Jeffrey Oskar Martínez González, Ángel Luis Lumbreras Bermejo, Carlos Antón Santos, Juan Miguel Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title | Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title_full | Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title_fullStr | Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title_full_unstemmed | Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title_short | Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry |
title_sort | healthcare workers hospitalized due to covid-19 have no higher risk of death than general population. data from the spanish semi-covid-19 registry |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894924/ https://www.ncbi.nlm.nih.gov/pubmed/33606820 http://dx.doi.org/10.1371/journal.pone.0247422 |
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