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Elective oocyte cryopreservation for age-related fertility decline
PURPOSE: Women who pursue fertility at an advanced age are increasingly common. Family planning and sexual education have traditionally focused on contraception and prevention of sexually transmitted diseases. A focus should now also be placed on fertility awareness and fertility preservation. This...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894970/ https://www.ncbi.nlm.nih.gov/pubmed/33608838 http://dx.doi.org/10.1007/s10815-021-02072-w |
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author | Chronopoulou, E. Raperport, C. Sfakianakis, A. Srivastava, G. Homburg, R. |
author_facet | Chronopoulou, E. Raperport, C. Sfakianakis, A. Srivastava, G. Homburg, R. |
author_sort | Chronopoulou, E. |
collection | PubMed |
description | PURPOSE: Women who pursue fertility at an advanced age are increasingly common. Family planning and sexual education have traditionally focused on contraception and prevention of sexually transmitted diseases. A focus should now also be placed on fertility awareness and fertility preservation. This manuscript aims to give an update on the existing evidence around elective oocyte cryopreservation, also highlighting the need for fertility education and evidence-based, individualized counselling. METHODS: A thorough electronic search was performed from the start of databases to March 2020 aiming to summarize the existing evidence around elective egg freezing, the logic behind its use, patient counselling and education, success rates and risks involved, regulation, cost-effectiveness, current status and future perspectives. RESULTS: Clinician-led counselling regarding reproductive aging and fertility preservation is often overlooked. Elective oocyte cryopreservation is not a guarantee of live birth, and the answer regarding cost-effectiveness needs to be individualized. The existing studies on obstetric and perinatal outcomes following the use of egg freezing are, until now, reassuring. Constant monitoring of short-term and long-term outcomes, uniform regulation and evidence-based, individualized counselling is of paramount importance. CONCLUSIONS: Elective oocyte cryopreservation is one of the most controversial aspects of the world of assisted reproduction, and a lot of questions remain unanswered. However, women today do have this option which was not available in the past. Elective oocyte cryopreservation for age-related fertility decline should be incorporated in women’s reproductive options to ensure informed decisions and reproductive autonomy. |
format | Online Article Text |
id | pubmed-7894970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-78949702021-02-22 Elective oocyte cryopreservation for age-related fertility decline Chronopoulou, E. Raperport, C. Sfakianakis, A. Srivastava, G. Homburg, R. J Assist Reprod Genet Opinion PURPOSE: Women who pursue fertility at an advanced age are increasingly common. Family planning and sexual education have traditionally focused on contraception and prevention of sexually transmitted diseases. A focus should now also be placed on fertility awareness and fertility preservation. This manuscript aims to give an update on the existing evidence around elective oocyte cryopreservation, also highlighting the need for fertility education and evidence-based, individualized counselling. METHODS: A thorough electronic search was performed from the start of databases to March 2020 aiming to summarize the existing evidence around elective egg freezing, the logic behind its use, patient counselling and education, success rates and risks involved, regulation, cost-effectiveness, current status and future perspectives. RESULTS: Clinician-led counselling regarding reproductive aging and fertility preservation is often overlooked. Elective oocyte cryopreservation is not a guarantee of live birth, and the answer regarding cost-effectiveness needs to be individualized. The existing studies on obstetric and perinatal outcomes following the use of egg freezing are, until now, reassuring. Constant monitoring of short-term and long-term outcomes, uniform regulation and evidence-based, individualized counselling is of paramount importance. CONCLUSIONS: Elective oocyte cryopreservation is one of the most controversial aspects of the world of assisted reproduction, and a lot of questions remain unanswered. However, women today do have this option which was not available in the past. Elective oocyte cryopreservation for age-related fertility decline should be incorporated in women’s reproductive options to ensure informed decisions and reproductive autonomy. Springer US 2021-02-19 2021-05 /pmc/articles/PMC7894970/ /pubmed/33608838 http://dx.doi.org/10.1007/s10815-021-02072-w Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature 2021 |
spellingShingle | Opinion Chronopoulou, E. Raperport, C. Sfakianakis, A. Srivastava, G. Homburg, R. Elective oocyte cryopreservation for age-related fertility decline |
title | Elective oocyte cryopreservation for age-related fertility decline |
title_full | Elective oocyte cryopreservation for age-related fertility decline |
title_fullStr | Elective oocyte cryopreservation for age-related fertility decline |
title_full_unstemmed | Elective oocyte cryopreservation for age-related fertility decline |
title_short | Elective oocyte cryopreservation for age-related fertility decline |
title_sort | elective oocyte cryopreservation for age-related fertility decline |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894970/ https://www.ncbi.nlm.nih.gov/pubmed/33608838 http://dx.doi.org/10.1007/s10815-021-02072-w |
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