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Mapping parameter spaces of biological switches
Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of multidimensional spaces of model parameters. Desp...
Autores principales: | Diegmiller, Rocky, Zhang, Lun, Gameiro, Marcio, Barr, Justinn, Imran Alsous, Jasmin, Schedl, Paul, Shvartsman, Stanislav Y., Mischaikow, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895388/ https://www.ncbi.nlm.nih.gov/pubmed/33556054 http://dx.doi.org/10.1371/journal.pcbi.1008711 |
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