Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

Receptor binding studies on sarbecoviruses would benefit from an available toolkit of recombinant spike proteins, or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric Receptor Binding Domain (RBD) proteins would be suitable candidates to...

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Detalles Bibliográficos
Autores principales: Bouwman, Kim M., Tomris, Ilhan, Turner, Hannah L., van der Woude, Roosmarijn, Shamorkina, Tatiana M., Bosman, Gerlof P., Rockx, Barry, Herfst, Sander, Snijder, Joost, Haagmans, Bart L., Ward, Andrew B., Boons, Geert-Jan, de Vries, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895411/
https://www.ncbi.nlm.nih.gov/pubmed/33556147
http://dx.doi.org/10.1371/journal.ppat.1009282

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