Cargando…

Role and clinical significance of TGF-β1 and TGF-βR1 in malignant tumors (Review)

The appearance and growth of malignant tumors is a complicated process that is regulated by a number of genes. In recent years, studies have revealed that the transforming growth factor-β (TGF-β) signaling pathway serves an important role in cell cycle regulation, growth and development, differentia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Junmin, Xiang, Hongjiao, Lu, Yifei, Wu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895515/ https://www.ncbi.nlm.nih.gov/pubmed/33604683 http://dx.doi.org/10.3892/ijmm.2021.4888

Ejemplares similares

TGF-β1 and TGFβR2 Gene Polymorphisms in Patients with Unstable Angina
por: Malinowski, Damian, et al.
Publicado: (2023)

Role of TGF-β 1 and TGF-β Type II Receptor in Gastric Cancer
por: Park, Dong Il, et al.
Publicado: (2002)

Polymorphisms of TGF-β1 and TGF-β3 in Chinese women with gestational diabetes mellitus
por: Xu, Yinglei, et al.
Publicado: (2020)

Fortilin interacts with TGF-β1 and prevents TGF-β receptor activation
por: Pinkaew, Decha, et al.
Publicado: (2022)

The Multifaceted Role of TGF-β in Gastrointestinal Tumors
por: Sabbadini, Fabio, et al.
Publicado: (2021)

Myofibroblastic stromal reaction and lymph node status in invasive breast carcinoma: possible role of the TGF-β1/TGF-βR1 pathway
por: Catteau, Xavier, et al.
Publicado: (2014)

TGF-β1 and TGF-β2 abundance in liver diseases of mice and men
por: Dropmann, Anne, et al.
Publicado: (2016)

Targeting TGFβR2‐mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer
por: Huang, Huocong, et al.
Publicado: (2019)

Inhibition of Wilms' Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway
por: Shi, Qinlin, et al.
Publicado: (2020)

Significance of the TGF-β1/IL-6 axis in oral cancer
por: Chen, Miao-Fen, et al.
Publicado: (2012)

Is Serum TGF-β1 and TGF-β2 levels Correlated to Children with Autism Intensity?
por: YOUSEFI, Jamshid, et al.
Publicado: (2021)

LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells
por: Li, Nian-Shuang, et al.
Publicado: (2015)

The role of TGF-β in the tumor microenvironment of pancreatic cancer
por: Luo, Qiang, et al.
Publicado: (2022)

The Transforming Growth Factor-β1 (TGF-β1) Gene Polymorphisms (TGF-β1 T869C and TGF-β1 T29C) and Susceptibility to Postmenopausal Osteoporosis: A Meta-Analysis
por: Sun, Jiajia, et al.
Publicado: (2015)

BMP1 controls TGFβ1 activation via cleavage of latent TGFβ-binding protein
por: Ge, Gaoxiang, et al.
Publicado: (2006)

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?
por: van Caam, A., et al.
Publicado: (2020)

HGF, sIL-6R and TGF-β(1) Play a Significant Role in the Progression of Multiple Myeloma
por: Jurczyszyn, Artur, et al.
Publicado: (2014)

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium
por: Flanders, Kathleen C., et al.
Publicado: (2016)

TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease
por: Kim, Sung Il, et al.
Publicado: (2012)

miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats
por: Li, Zhuanjian, et al.
Publicado: (2017)

The Role of TGF-β Receptors in Fibrosis
por: Nakerakanti, Sashidhar, et al.
Publicado: (2012)

The Role of TGF-β in Bone Metastases
por: Trivedi, Trupti, et al.
Publicado: (2021)

Detection of serum MCP-1 and TGF-β1 in polymyositis/dermatomyositis patients and its significance
por: Wu, Chun-Ye, et al.
Publicado: (2019)

Mysteries of TGF-β Paradox in Benign and Malignant Cells
por: Zhang, Qiang, et al.
Publicado: (2014)

Biological Activity Differences between TGF-β1 and TGF-β3 Correlate with Differences in the Rigidity and Arrangement of Their Component Monomers
por: Huang, Tao, et al.
Publicado: (2014)

Absence of integrin-mediated TGFβ1 activation in vivo recapitulates the phenotype of TGFβ1-null mice
por: Yang, Zhiwei, et al.
Publicado: (2007)

TGF-β1-Mediated FDNCR1 Regulates Porcine Preadipocyte Differentiation via the TGF-β Signaling Pathway
por: Zhang, Zhe, et al.
Publicado: (2020)

The Pro-inflammatory Role of TGFβ1: A Paradox?
por: Han, Gangwen, et al.
Publicado: (2012)

Liberating TGFβ
por: Leslie, Mitch
Publicado: (2007)

TGF-β Signaling
por: Tzavlaki, Kalliopi, et al.
Publicado: (2020)

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung
por: Sureshbabu, Angara, et al.
Publicado: (2015)

The miR-130a-3p/TGF-βRII Axis Participates in Inhibiting the Differentiation of Fibroblasts Induced by TGF-β1
por: Liu, Yanhong, et al.
Publicado: (2021)

Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon’s fibroblasts: An in vitro study
por: Noh, Siti Munirah Md, et al.
Publicado: (2015)

EHF promotes colorectal carcinoma progression by activating TGF‐β1 transcription and canonical TGF‐β signaling
por: Wang, Lan, et al.
Publicado: (2020)

Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2
por: Halbgebauer, D., et al.
Publicado: (2021)

Status of higher TGF-β1 and TGF-β2 levels in the aqueous humour of patients with diabetes and cataracts
por: Gao, Chao, et al.
Publicado: (2022)

Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
por: Wei, Ting, et al.
Publicado: (2022)

Erratum: miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats
por: Li, Zhuanjian, et al.
Publicado: (2018)

TGF-β signaling in the tumor metabolic microenvironment and targeted therapies
por: Shi, Xueke, et al.
Publicado: (2022)

TGF-β1 gene − 509C > T promoter polymorphism modulates TGF-β1 levels in hepatitis E patients
por: Rathod, Sanjay B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9j9ec152gr8t1sqclgdh3liaa1