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[D-Ala(2), D-Leu(5)] Enkephalin Inhibits TLR4/NF-κB Signaling Pathway and Protects Rat Brains against Focal Ischemia-Reperfusion Injury

BACKGROUND: Cerebral ischemia-reperfusion (I/R) injury is the main cause of acute brain injury, which is a life-threatening disease due to the lack of effective treatments. [D-Ala(2), D-Leu(5)] enkephalin (DADLE) is a synthetic delta-opioid receptor agonist that is reported to confer neuroprotective...

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Detalles Bibliográficos
Autores principales:	Fu, Danyun, Liu, Haitong, Zhu, Jiang, Xu, Hongjiao, Yao, Junyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895595/ https://www.ncbi.nlm.nih.gov/pubmed/33628116 http://dx.doi.org/10.1155/2021/6661620

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