Cargando…

An unusual cause of fever and jaundice

A 52 year old previously healthy woman from Mumbai presented with fever and jaundice of 10 days duration. At admission, she was jaundiced with tachycardia, tachypnea, hypoxia, hypotension, conjunctival congestion and mild erythematous flush over the skin. She had very high WBC counts and CRP's...

Descripción completa

Detalles Bibliográficos
Autores principales: Varyani, Umesh, Singhal, Tanu, Sheth, Sharad, Shetty, Kiran, Harshe, Pradnya, Shah, Sweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895698/
https://www.ncbi.nlm.nih.gov/pubmed/33617927
http://dx.doi.org/10.1016/j.ijmmb.2021.02.001
Descripción
Sumario:A 52 year old previously healthy woman from Mumbai presented with fever and jaundice of 10 days duration. At admission, she was jaundiced with tachycardia, tachypnea, hypoxia, hypotension, conjunctival congestion and mild erythematous flush over the skin. She had very high WBC counts and CRP's with direct hyperbilirubinemia and azotemia. Investigations for infectious causes of fever were negative. RT-PCR for SARS-CoV-2 in the nasopharynx was negative. However her SARS-CoV-2 antibodies were reactive. She also had echocardiographic and biochemical evidence of cardiac dysfunction. The diagnosis of Multisystem inflammatory syndrome–Adult (MIS-A) was thus established. She rapidly improved with intravenous immunoglobulin (2 gm/kg) and high dose steroids.