Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma

Many metabolic pathways, including lipid metabolism, are rewired in tumors to support energy and biomass production and to allow adaptation to stressful environments. Neuroblastoma is the second deadliest solid tumor in children. Genetic aberrations, as the amplification of the MYCN-oncogene, correl...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz-Pérez, María Victoria, Sainero-Alcolado, Lourdes, Oliynyk, Ganna, Matuschek, Isabell, Balboni, Nicola, Ubhayasekera, S.J. Kumari A., Snaebjornsson, Marteinn Thor, Makowski, Kamil, Aaltonen, Kristina, Bexell, Daniel, Serra, Dolors, Nilsson, Roland, Bergquist, Jonas, Schulze, Almut, Arsenian-Henriksson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895756/
https://www.ncbi.nlm.nih.gov/pubmed/33659885
http://dx.doi.org/10.1016/j.isci.2021.102128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895756/
https://www.ncbi.nlm.nih.gov/pubmed/33659885
http://dx.doi.org/10.1016/j.isci.2021.102128

Ejemplares similares