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Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma
Many metabolic pathways, including lipid metabolism, are rewired in tumors to support energy and biomass production and to allow adaptation to stressful environments. Neuroblastoma is the second deadliest solid tumor in children. Genetic aberrations, as the amplification of the MYCN-oncogene, correl...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895756/ https://www.ncbi.nlm.nih.gov/pubmed/33659885 http://dx.doi.org/10.1016/j.isci.2021.102128 |