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The catalytic mechanism of vitamin K epoxide reduction in a cellular environment

Vitamin K epoxide reductases (VKORs) constitute a major family of integral membrane thiol oxidoreductases. In humans, VKOR sustains blood coagulation and bone mineralization through the vitamin K cycle. Previous chemical models assumed that the catalysis of human VKOR (hVKOR) starts from a fully red...

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Detalles Bibliográficos
Autores principales:	Shen, Guomin, Cui, Weidong, Cao, Qing, Gao, Meng, Liu, Hongli, Su, Gaigai, Gross, Michael L., Li, Weikai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895805/ https://www.ncbi.nlm.nih.gov/pubmed/33273012 http://dx.doi.org/10.1074/jbc.RA120.015401

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