SHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling

Dysfunction of the Hippo pathway enables cells to evade contact inhibition and provides advantages for cancerous overgrowth. However, for a significant portion of human cancer, how Hippo signaling is perturbed remains unknown. To answer this question, we performed a genome-wide screening for genes t...

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Detalles Bibliográficos
Autores principales: Xu, Liang, Li, Peixue, Hao, Xue, Lu, Yi, Liu, Mingxian, Song, Wenqian, Shan, Lin, Yu, Jiao, Ding, Hongyu, Chen, Shishuang, Yang, Ailing, Zeng, Yi Arial, Zhang, Lei, Jiang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895894/
https://www.ncbi.nlm.nih.gov/pubmed/32661924
http://dx.doi.org/10.1007/s13238-020-00742-6

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