Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice

Post-zygotic mutations that generate tissue mosaicism are increasingly associated with severe congenital defects, including those arising from failed neural tube closure. Here we report that neural fold elevation during mouse spinal neurulation is vulnerable to deletion of the VANGL planar cell pola...

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Detalles Bibliográficos
Autores principales: Galea, Gabriel L., Maniou, Eirini, Edwards, Timothy J., Marshall, Abigail R., Ampartzidis, Ioakeim, Greene, Nicholas D. E., Copp, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895924/
https://www.ncbi.nlm.nih.gov/pubmed/33608529
http://dx.doi.org/10.1038/s41467-021-21372-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895924/
https://www.ncbi.nlm.nih.gov/pubmed/33608529
http://dx.doi.org/10.1038/s41467-021-21372-4

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