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Robust inference of kinase activity using functional networks

Mass spectrometry enables high-throughput screening of phosphoproteins across a broad range of biological contexts. When complemented by computational algorithms, phospho-proteomic data allows the inference of kinase activity, facilitating the identification of dysregulated kinases in various diseas...

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Detalles Bibliográficos
Autores principales: Yılmaz, Serhan, Ayati, Marzieh, Schlatzer, Daniela, Çiçek, A. Ercüment, Chance, Mark R., Koyutürk, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895941/
https://www.ncbi.nlm.nih.gov/pubmed/33608514
http://dx.doi.org/10.1038/s41467-021-21211-6