MTBP phosphorylation controls DNA replication origin firing

Faithful genome duplication requires regulation of origin firing to determine loci, timing and efficiency of replisome generation. Established kinase targets for eukaryotic origin firing regulation are the Mcm2-7 helicase, Sld3/Treslin/TICRR and Sld2/RecQL4. We report that metazoan Sld7, MTBP (Mdm2...

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Detalles Bibliográficos
Autores principales: Ferreira, Pedro, Höfer, Verena, Kronshage, Nora, Marko, Anika, Reusswig, Karl-Uwe, Tetik, Bilal, Dießel, Christoph, Köhler, Kerstin, Tschernoster, Nikolai, Altmüller, Janine, Schulze, Nina, Pfander, Boris, Boos, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895959/
https://www.ncbi.nlm.nih.gov/pubmed/33608586
http://dx.doi.org/10.1038/s41598-021-83287-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895959/
https://www.ncbi.nlm.nih.gov/pubmed/33608586
http://dx.doi.org/10.1038/s41598-021-83287-w

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