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Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

Genome engineering using CRISPR/Cas9 technology enables simple, efficient and precise genomic modifications in human cells. Conventional immortalized cell lines can be easily edited or screened using genome-wide libraries with lentiviral transduction. However, cell types derived from the differentia...

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Detalles Bibliográficos
Autores principales:	Navarro-Guerrero, Elena, Tay, Chwen, Whalley, Justin P., Cowley, Sally A., Davies, Ben, Knight, Julian C., Ebner, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895961/ https://www.ncbi.nlm.nih.gov/pubmed/33608581 http://dx.doi.org/10.1038/s41598-021-82137-z

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