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Ex vivo visualization of RNA polymerase III-specific gene activity with electron microscopy
The direct study of transcription or DNA–protein-binding events, requires imaging of individual genes at molecular resolution. Electron microscopy (EM) can show local detail of the genome. However, direct visualization and analysis of specific individual genes is currently not feasible as they canno...
Autores principales: | Manger, Sina, Ermel, Utz H., Frangakis, Achilleas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895982/ https://www.ncbi.nlm.nih.gov/pubmed/33608618 http://dx.doi.org/10.1038/s42003-021-01752-8 |
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