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Differentiating cancer cells reveal early large-scale genome regulation by pericentric domains
Finding out how cells prepare for fate change during differentiation commitment was our task. To address whether the constitutive pericentromere-associated domains (PADs) may be involved, we used a model system with known transcriptome data, MCF-7 breast cancer cells treated with the ErbB3 ligand he...
Autores principales: | Krigerts, Jekabs, Salmina, Kristine, Freivalds, Talivaldis, Zayakin, Pawel, Rumnieks, Felikss, Inashkina, Inna, Giuliani, Alessandro, Hausmann, Michael, Erenpreisa, Jekaterina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896032/ https://www.ncbi.nlm.nih.gov/pubmed/33453273 http://dx.doi.org/10.1016/j.bpj.2021.01.002 |
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