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Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor

Ligand-activated signaling through the type 1 insulin-like growth factor receptor (IGF1R) is implicated in many physiological processes ranging from normal human growth to cancer proliferation and metastasis. IGF1R has also emerged as a target for receptor-mediated transcytosis, a transport phenomen...

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Detalles Bibliográficos
Autores principales:	Sheff, Joey, Wang, Ping, Xu, Ping, Arbour, Melanie, Masson, Luke, van Faassen, Henk, Hussack, Greg, Kemmerich, Kristin, Brunette, Eric, Stanimirovic, Danica, Hill, Jennifer J., Kelly, John, Ni, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896052/ https://www.ncbi.nlm.nih.gov/pubmed/33608571 http://dx.doi.org/10.1038/s41598-021-83198-w

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