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Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines

In 21 st century, nanomedicine has turned out to be an emergent modulus operation for the diagnosis and treatment for cancer. The current study includes the Green synthesis of zinc oxide nanoparticles (ZnO NPs) from the leaves of Raphanus sativus var. Longipinnatus and interpretation of its anticanc...

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Autores principales: Umamaheswari, A., Prabu, S. Lakshmana, John, S. Adharsh, Puratchikody, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896141/
https://www.ncbi.nlm.nih.gov/pubmed/33659193
http://dx.doi.org/10.1016/j.btre.2021.e00595
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author Umamaheswari, A.
Prabu, S. Lakshmana
John, S. Adharsh
Puratchikody, A.
author_facet Umamaheswari, A.
Prabu, S. Lakshmana
John, S. Adharsh
Puratchikody, A.
author_sort Umamaheswari, A.
collection PubMed
description In 21 st century, nanomedicine has turned out to be an emergent modulus operation for the diagnosis and treatment for cancer. The current study includes the Green synthesis of zinc oxide nanoparticles (ZnO NPs) from the leaves of Raphanus sativus var. Longipinnatus and interpretation of its anticancer activity. Synthesized ZnO NPs were investigated by UV–vis, FTIR, particle size analysis, SEM, XRD and its anticancer activity using A549 cell lines. The UV–vis and particle size confirmed the developed ZnO NPs are in nanoscale. The FTIR studies confirmed the presence of various functional groups. SEM and XRD pictures confirmed the partial crystal spherical shape and wurtzite crystal nature. The cytotoxicity results pointed out the enhanced cytotoxic effect of the synthesized ZnO NPs. This is the first attempt of Raphanus sativus var. Longipinnatus facilitated synthesis of ZnO NPs as anticancer agents and may subsequently be potential chemopreventive agent against other cancer treatment in future.
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spelling pubmed-78961412021-03-02 Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines Umamaheswari, A. Prabu, S. Lakshmana John, S. Adharsh Puratchikody, A. Biotechnol Rep (Amst) Research Article In 21 st century, nanomedicine has turned out to be an emergent modulus operation for the diagnosis and treatment for cancer. The current study includes the Green synthesis of zinc oxide nanoparticles (ZnO NPs) from the leaves of Raphanus sativus var. Longipinnatus and interpretation of its anticancer activity. Synthesized ZnO NPs were investigated by UV–vis, FTIR, particle size analysis, SEM, XRD and its anticancer activity using A549 cell lines. The UV–vis and particle size confirmed the developed ZnO NPs are in nanoscale. The FTIR studies confirmed the presence of various functional groups. SEM and XRD pictures confirmed the partial crystal spherical shape and wurtzite crystal nature. The cytotoxicity results pointed out the enhanced cytotoxic effect of the synthesized ZnO NPs. This is the first attempt of Raphanus sativus var. Longipinnatus facilitated synthesis of ZnO NPs as anticancer agents and may subsequently be potential chemopreventive agent against other cancer treatment in future. Elsevier 2021-02-05 /pmc/articles/PMC7896141/ /pubmed/33659193 http://dx.doi.org/10.1016/j.btre.2021.e00595 Text en © 2021 Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Umamaheswari, A.
Prabu, S. Lakshmana
John, S. Adharsh
Puratchikody, A.
Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title_full Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title_fullStr Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title_full_unstemmed Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title_short Green synthesis of zinc oxide nanoparticles using leaf extracts of Raphanus sativus var. Longipinnatus and evaluation of their anticancer property in A549 cell lines
title_sort green synthesis of zinc oxide nanoparticles using leaf extracts of raphanus sativus var. longipinnatus and evaluation of their anticancer property in a549 cell lines
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896141/
https://www.ncbi.nlm.nih.gov/pubmed/33659193
http://dx.doi.org/10.1016/j.btre.2021.e00595
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