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Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation

Immunoglobulin (Ig) G molecules are essential players in the human immune response against bacterial infections. An important effector of IgG-dependent immunity is the induction of complement activation, a reaction that triggers a variety of responses that help kill bacteria. Antibody-dependent comp...

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Detalles Bibliográficos
Autores principales: Cruz, Ana Rita, den Boer, Maurits A., Strasser, Jürgen, Zwarthoff, Seline A., Beurskens, Frank J., de Haas, Carla J. C., Aerts, Piet C., Wang, Guanbo, de Jong, Rob N., Bagnoli, Fabio, van Strijp, Jos A. G., van Kessel, Kok P. M., Schuurman, Janine, Preiner, Johannes, Heck, Albert J. R., Rooijakkers, Suzan H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896290/
https://www.ncbi.nlm.nih.gov/pubmed/33563762
http://dx.doi.org/10.1073/pnas.2016772118