CD20 as a gatekeeper of the resting state of human B cells

CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies for B cell depletion therapies, the biological function of their target remains unclear. Here, we demonstrate that CD20 controls the nanoscale o...

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Detalles Bibliográficos
Autores principales: Kläsener, Kathrin, Jellusova, Julia, Andrieux, Geoffroy, Salzer, Ulrich, Böhler, Chiara, Steiner, Sebastian N., Albinus, Jonas B., Cavallari, Marco, Süß, Beatrix, Voll, Reinhard E., Boerries, Melanie, Wollscheid, Bernd, Reth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896350/
https://www.ncbi.nlm.nih.gov/pubmed/33563755
http://dx.doi.org/10.1073/pnas.2021342118

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