ARID1A genomic alterations driving microsatellite instability through somatic MLH1 methylation with response to immunotherapy in metastatic lung adenocarcinoma: a case report

BACKGROUND: Tumor molecular screening allows categorization of molecular alterations to select the best therapeutic strategy. AT-rich interactive domain-containing 1A (ARID1A) gene mutations are present in gastric, endometrial, and clear cell ovarian tumors. Inactivation of this gene impairs mismatc...

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Detalles Bibliográficos
Autores principales: Durán, Mercedes, Faull, Iris, Lastra, Enrique, Laes, Jean-Francois, Rodrigo, Ana Belén, Sánchez-Escribano, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896399/
https://www.ncbi.nlm.nih.gov/pubmed/33608032
http://dx.doi.org/10.1186/s13256-020-02589-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896399/
https://www.ncbi.nlm.nih.gov/pubmed/33608032
http://dx.doi.org/10.1186/s13256-020-02589-1

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