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Transport mechanisms of SARS-CoV-E viroporin in calcium solutions: Lipid-dependent Anomalous Mole Fraction Effect and regulation of pore conductance
The envelope protein E of the SARS-CoV coronavirus is an archetype of viroporin. It is a small hydrophobic protein displaying ion channel activity that has proven highly relevant in virus-host interaction and virulence. Ion transport through E channel was shown to alter Ca(2+) homeostasis in the cel...
Autores principales: | Verdiá-Báguena, Carmina, Aguilella, Vicente M., Queralt-Martín, María, Alcaraz, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896491/ https://www.ncbi.nlm.nih.gov/pubmed/33621516 http://dx.doi.org/10.1016/j.bbamem.2021.183590 |
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