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Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics

OBJECTIVES: To report on the disease-related quality of life of patients living with diabetes mellitus in Rwanda and identify its predictors. DESIGN: Cross-sectional study, part of the baseline assessment of a cluster-randomised controlled trial. SETTING: Outpatient clinics for non-communicable dise...

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Autores principales: Lygidakis, Charilaos, Uwizihiwe, Jean Paul, Bia, Michela, Uwinkindi, Francois, Kallestrup, Per, Vögele, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896598/
https://www.ncbi.nlm.nih.gov/pubmed/33608403
http://dx.doi.org/10.1136/bmjopen-2020-043997
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author Lygidakis, Charilaos
Uwizihiwe, Jean Paul
Bia, Michela
Uwinkindi, Francois
Kallestrup, Per
Vögele, Claus
author_facet Lygidakis, Charilaos
Uwizihiwe, Jean Paul
Bia, Michela
Uwinkindi, Francois
Kallestrup, Per
Vögele, Claus
author_sort Lygidakis, Charilaos
collection PubMed
description OBJECTIVES: To report on the disease-related quality of life of patients living with diabetes mellitus in Rwanda and identify its predictors. DESIGN: Cross-sectional study, part of the baseline assessment of a cluster-randomised controlled trial. SETTING: Outpatient clinics for non-communicable diseases of nine hospitals across Rwanda. PARTICIPANTS: Between January and August 2019, 206 patients were recruited as part of the clinical trial. Eligible participants were those aged 21–80 years and with a diagnosis of diabetes mellitus for at least 6 months. Illiterate patients, those with severe hearing or visual impairments, those with severe mental health conditions, terminally ill, and those pregnant or in the postpartum period were excluded PRIMARY AND SECONDARY OUTCOME MEASURES: Disease-specific quality of life was measured with the Kinyarwanda version of the Diabetes-39 (D-39) questionnaire. A glycated haemoglobin (HbA1c) test was performed on all patients. Sociodemographic and clinical data were collected, including medical history, disease-related complications and comorbidities. RESULTS: The worst affected dimensions of the D-39 were ‘anxiety and worry’ (mean=51.63, SD=25.51), ‘sexual functioning’ (mean=44.58, SD=37.02), and ‘energy and mobility’ (mean=42.71, SD=20.69). Duration of the disease and HbA1c values were not correlated with any of the D-39 dimensions. A moderating effect was identified between use of insulin and achieving a target HbA1c of 7% in the ‘diabetes control’ scale. The most frequent comorbidity was hypertension (49.0% of participants), which had a greater negative effect on the ‘diabetes control’ and ‘social burden’ scales in women. Higher education was a predictor of less impact on the ‘social burden’ and ‘energy and mobility’ scales. CONCLUSIONS: Several variables were identified as predictors for the five dimensions of quality of life that were studied, providing opportunities for tailored preventive programmes. Further prospective studies are needed to determine causal relationships. TRIAL REGISTRATION NUMBER: NCT03376607.
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spelling pubmed-78965982021-03-05 Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics Lygidakis, Charilaos Uwizihiwe, Jean Paul Bia, Michela Uwinkindi, Francois Kallestrup, Per Vögele, Claus BMJ Open Global Health OBJECTIVES: To report on the disease-related quality of life of patients living with diabetes mellitus in Rwanda and identify its predictors. DESIGN: Cross-sectional study, part of the baseline assessment of a cluster-randomised controlled trial. SETTING: Outpatient clinics for non-communicable diseases of nine hospitals across Rwanda. PARTICIPANTS: Between January and August 2019, 206 patients were recruited as part of the clinical trial. Eligible participants were those aged 21–80 years and with a diagnosis of diabetes mellitus for at least 6 months. Illiterate patients, those with severe hearing or visual impairments, those with severe mental health conditions, terminally ill, and those pregnant or in the postpartum period were excluded PRIMARY AND SECONDARY OUTCOME MEASURES: Disease-specific quality of life was measured with the Kinyarwanda version of the Diabetes-39 (D-39) questionnaire. A glycated haemoglobin (HbA1c) test was performed on all patients. Sociodemographic and clinical data were collected, including medical history, disease-related complications and comorbidities. RESULTS: The worst affected dimensions of the D-39 were ‘anxiety and worry’ (mean=51.63, SD=25.51), ‘sexual functioning’ (mean=44.58, SD=37.02), and ‘energy and mobility’ (mean=42.71, SD=20.69). Duration of the disease and HbA1c values were not correlated with any of the D-39 dimensions. A moderating effect was identified between use of insulin and achieving a target HbA1c of 7% in the ‘diabetes control’ scale. The most frequent comorbidity was hypertension (49.0% of participants), which had a greater negative effect on the ‘diabetes control’ and ‘social burden’ scales in women. Higher education was a predictor of less impact on the ‘social burden’ and ‘energy and mobility’ scales. CONCLUSIONS: Several variables were identified as predictors for the five dimensions of quality of life that were studied, providing opportunities for tailored preventive programmes. Further prospective studies are needed to determine causal relationships. TRIAL REGISTRATION NUMBER: NCT03376607. BMJ Publishing Group 2021-02-19 /pmc/articles/PMC7896598/ /pubmed/33608403 http://dx.doi.org/10.1136/bmjopen-2020-043997 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Global Health
Lygidakis, Charilaos
Uwizihiwe, Jean Paul
Bia, Michela
Uwinkindi, Francois
Kallestrup, Per
Vögele, Claus
Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title_full Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title_fullStr Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title_full_unstemmed Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title_short Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
title_sort quality of life among adult patients living with diabetes in rwanda: a cross-sectional study in outpatient clinics
topic Global Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896598/
https://www.ncbi.nlm.nih.gov/pubmed/33608403
http://dx.doi.org/10.1136/bmjopen-2020-043997
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