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Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult

A 34year-old man presented with diminution of vision, pain and whitish opacity in both eyes (right eye followed by left eye) since 1 week. He is a known case of chronic alcoholic abuse. He had multiple episodes of haemoptysis in the past. On general physical examination, he was severely malnourished...

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Autores principales: Lata, Suman, Bafna, Rahul Kumar, Asif, Mohamed Ibrahime, Sachan, Anusha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896612/
https://www.ncbi.nlm.nih.gov/pubmed/33608333
http://dx.doi.org/10.1136/bcr-2020-237343
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author Lata, Suman
Bafna, Rahul Kumar
Asif, Mohamed Ibrahime
Sachan, Anusha
author_facet Lata, Suman
Bafna, Rahul Kumar
Asif, Mohamed Ibrahime
Sachan, Anusha
author_sort Lata, Suman
collection PubMed
description A 34year-old man presented with diminution of vision, pain and whitish opacity in both eyes (right eye followed by left eye) since 1 week. He is a known case of chronic alcoholic abuse. He had multiple episodes of haemoptysis in the past. On general physical examination, he was severely malnourished with multiple oral ulcers. Visual acuity at presentation was light perception in both eyes with projection of rays accurate in all quadrants. Slit-lamp biomicroscopy revealed bilateral total corneal melt with diffuse conjunctival congestion. Corneal scrapings and blood investigations were done and he was started on empirical topical and systemic therapy followed by surgical intervention, with large corneal grafts in both the eyes (right eye followed by left eye) with 1 day interval. The visual gain in both the eyes were 20/400 at first postoperative day. The right eye developed severe fibrinous reaction on the second postoperative day which resolved with topical antibiotics, topical steroids and systemic steroids. The patient was followed up via telemedicine (due to COVID-19 outbreak) and he is able to carry out his daily routine work independently.
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spelling pubmed-78966122021-03-05 Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult Lata, Suman Bafna, Rahul Kumar Asif, Mohamed Ibrahime Sachan, Anusha BMJ Case Rep Case Report A 34year-old man presented with diminution of vision, pain and whitish opacity in both eyes (right eye followed by left eye) since 1 week. He is a known case of chronic alcoholic abuse. He had multiple episodes of haemoptysis in the past. On general physical examination, he was severely malnourished with multiple oral ulcers. Visual acuity at presentation was light perception in both eyes with projection of rays accurate in all quadrants. Slit-lamp biomicroscopy revealed bilateral total corneal melt with diffuse conjunctival congestion. Corneal scrapings and blood investigations were done and he was started on empirical topical and systemic therapy followed by surgical intervention, with large corneal grafts in both the eyes (right eye followed by left eye) with 1 day interval. The visual gain in both the eyes were 20/400 at first postoperative day. The right eye developed severe fibrinous reaction on the second postoperative day which resolved with topical antibiotics, topical steroids and systemic steroids. The patient was followed up via telemedicine (due to COVID-19 outbreak) and he is able to carry out his daily routine work independently. BMJ Publishing Group 2021-02-19 /pmc/articles/PMC7896612/ /pubmed/33608333 http://dx.doi.org/10.1136/bcr-2020-237343 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Case Report
Lata, Suman
Bafna, Rahul Kumar
Asif, Mohamed Ibrahime
Sachan, Anusha
Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title_full Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title_fullStr Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title_full_unstemmed Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title_short Bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin A deficiency in the adult
title_sort bilateral liquefactive corneal necrosis: a rare and devastating complication of vitamin a deficiency in the adult
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896612/
https://www.ncbi.nlm.nih.gov/pubmed/33608333
http://dx.doi.org/10.1136/bcr-2020-237343
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