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Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report
BACKGROUND: In clinical work, 85%-90% of malignant thyroid diseases are papillary thyroid cancer (PTC); thus, clinicians neglect other types of thyroid cancer, such as medullary thyroid carcinoma (MTC). CASE SUMMARY: We report a 53-year-old female patient with a preoperative calcitonin level of 345...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896685/ https://www.ncbi.nlm.nih.gov/pubmed/33644201 http://dx.doi.org/10.12998/wjcc.v9.i6.1343 |
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author | Gan, Feng-Jiao Zhou, Tie Wu, Shun Xu, Meng-Xi Sun, Su-Hong |
author_facet | Gan, Feng-Jiao Zhou, Tie Wu, Shun Xu, Meng-Xi Sun, Su-Hong |
author_sort | Gan, Feng-Jiao |
collection | PubMed |
description | BACKGROUND: In clinical work, 85%-90% of malignant thyroid diseases are papillary thyroid cancer (PTC); thus, clinicians neglect other types of thyroid cancer, such as medullary thyroid carcinoma (MTC). CASE SUMMARY: We report a 53-year-old female patient with a preoperative calcitonin level of 345 pg/mL. There was no definitive diagnosis of MTC by preoperative fine-needle aspiration cytology or intraoperative frozen pathology, but the presence of PTC and MTC was confirmed by postoperative paraffin pathology. The patient underwent total thyroidectomy and bilateral central lymph node dissection. Close follow-up at 1.5 years after surgery revealed no signs of recurrence or metastasis. CONCLUSION: The issue in clinical work-up regarding types of thyroid cancer provides a novel and challenging idea for the surgical treatment of MTC. In the absence of central lymph node metastasis, it is worth addressing whether patients with high calcitonin can undergo total thyroidectomy and bilateral central lymph node dissection without bilateral lateral neck lymph node dissection. |
format | Online Article Text |
id | pubmed-7896685 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-78966852021-02-26 Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report Gan, Feng-Jiao Zhou, Tie Wu, Shun Xu, Meng-Xi Sun, Su-Hong World J Clin Cases Case Report BACKGROUND: In clinical work, 85%-90% of malignant thyroid diseases are papillary thyroid cancer (PTC); thus, clinicians neglect other types of thyroid cancer, such as medullary thyroid carcinoma (MTC). CASE SUMMARY: We report a 53-year-old female patient with a preoperative calcitonin level of 345 pg/mL. There was no definitive diagnosis of MTC by preoperative fine-needle aspiration cytology or intraoperative frozen pathology, but the presence of PTC and MTC was confirmed by postoperative paraffin pathology. The patient underwent total thyroidectomy and bilateral central lymph node dissection. Close follow-up at 1.5 years after surgery revealed no signs of recurrence or metastasis. CONCLUSION: The issue in clinical work-up regarding types of thyroid cancer provides a novel and challenging idea for the surgical treatment of MTC. In the absence of central lymph node metastasis, it is worth addressing whether patients with high calcitonin can undergo total thyroidectomy and bilateral central lymph node dissection without bilateral lateral neck lymph node dissection. Baishideng Publishing Group Inc 2021-02-26 2021-02-26 /pmc/articles/PMC7896685/ /pubmed/33644201 http://dx.doi.org/10.12998/wjcc.v9.i6.1343 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Gan, Feng-Jiao Zhou, Tie Wu, Shun Xu, Meng-Xi Sun, Su-Hong Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title | Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title_full | Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title_fullStr | Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title_full_unstemmed | Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title_short | Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? A case report |
title_sort | do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance? a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896685/ https://www.ncbi.nlm.nih.gov/pubmed/33644201 http://dx.doi.org/10.12998/wjcc.v9.i6.1343 |
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