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PolG Inhibits Gastric Cancer Glycolysis and Viability by Suppressing PKM2 Phosphorylation
PURPOSE: Gastric cancer (GC) is the fifth most frequently diagnosed cancer and the third leading cause of cancer-related death. There is a critical need for the development of novel therapies in GC. DNA polymerase gamma (PolG) has been implicated in mitochondrial homeostasis and affects the developm...
Autores principales: | Lv, Mengzhu, Zhang, Simeng, Dong, Yuqing, Cao, Liu, Guo, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896732/ https://www.ncbi.nlm.nih.gov/pubmed/33623435 http://dx.doi.org/10.2147/CMAR.S292306 |
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