Involvement of 5-Hydroxytryptamine Receptor 2A in the Pathophysiology of Medication-Overuse Headache

BACKGROUND: Recent studies indicated that analgesic overuse upregulated 5-hydroxytryptamine receptor 2A (5-HT(2A)R) and subsequently activated nitric oxide synthase (NOS) and thus induced latent sensitization, which provided a mechanistic basis for medication-overuse headache (MOH). Moreover, glycog...

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Detalles Bibliográficos
Autores principales: Zheng, Zhenyang, Shi, Xiaolei, Xiang, Yue, Zhang, Aiwu, Fang, Yannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896776/
https://www.ncbi.nlm.nih.gov/pubmed/33623427
http://dx.doi.org/10.2147/JPR.S283734

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