Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss

Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free therapeutics involving MSCs and the contents can be customized under disease-associated microenvironments. However, optimal MSC-preconditioning to enhance its therapeutic potential is largely unknown. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Nakao, Yuki, Fukuda, Takao, Zhang, Qunzhou, Sanui, Terukazu, Shinjo, Takanori, Kou, Xiaoxing, Chen, Chider, Liu, Dawei, Watanabe, Yukari, Hayashi, Chikako, Yamato, Hiroaki, Yotsumoto, Karen, Tanaka, Urara, Taketomi, Takaharu, Uchiumi, Takeshi, Le, Anh D., Shi, Songtao, Nishimura, Fusanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897289/
https://www.ncbi.nlm.nih.gov/pubmed/33359765
http://dx.doi.org/10.1016/j.actbio.2020.12.046

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