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Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation

BACKGROUND: This study aimed to explore the effects of ceramide (Cer) on NLRP3 inflammasome activation and their underlying mechanisms. METHODS: Lipopolysaccharide (LPS)/adenosine triphosphate (ATP)-induced NLRP3 inflammasome activation in J774A.1 cells and THP-1 macrophages was used as an in vitro...

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Detalles Bibliográficos
Autores principales:	Jiang, Jianjun, Shi, Yining, Cao, Jiyu, Lu, Youjin, Sun, Gengyun, Yang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897379/ https://www.ncbi.nlm.nih.gov/pubmed/33612104 http://dx.doi.org/10.1186/s12944-021-01446-4

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