Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells

BACKGROUND: Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in progression of tumours, including gliomas. The aim was to i...

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Detalles Bibliográficos
Autores principales: de los Santos-Jiménez, Juan, Campos-Sandoval, José A., Márquez-Torres, Clara, Urbano-Polo, Nieves, Brøndegaard, David, Martín-Rufián, Mercedes, Lobo, Carolina, Peñalver, Ana, Gómez-García, María C., Martín-Campos, Janet, Cardona, Carolina, Castilla, Laura, da Costa Souza, Felipe, Cheng, Tzuling, Segura, Juan A., Alonso, Francisco J., Curi, Rui, Colquhoun, Alison, DeBerardinis, Ralph J., Márquez, Javier, Matés, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897386/
https://www.ncbi.nlm.nih.gov/pubmed/33610185
http://dx.doi.org/10.1186/s12929-021-00712-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897386/
https://www.ncbi.nlm.nih.gov/pubmed/33610185
http://dx.doi.org/10.1186/s12929-021-00712-y

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