Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit

BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently discovered autoimmune syndrome associated with psychosis, dyskinesia, and seizures. However, the underlying mechanisms of this disease remain unclear, in part because of a lack of suitable animal models. METHODS: This...

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Detalles Bibliográficos
Autores principales: Ding, Yuewen, Zhou, Zheye, Chen, Jinyu, Peng, Yu, Wang, Haitao, Qiu, Wei, Xie, Wei, Zhang, Jun, Wang, Honghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897387/
https://www.ncbi.nlm.nih.gov/pubmed/33612107
http://dx.doi.org/10.1186/s12974-021-02107-0

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