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Inflammatory arthritis in patients with COVID-19
Patients with inflammatory arthritis represent a possible high-risk group to COVID-19 due to their immunosuppressive regimen designed to maintain low disease activity. Thus, substantial effort has been put forth to understand the impact of COVID-19 on these patients. Patients with rheumatic diseases...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897406/ https://www.ncbi.nlm.nih.gov/pubmed/33626415 http://dx.doi.org/10.1016/j.trsl.2021.02.010 |
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author | Conway, Richard Konig, Maximilian F. Graef, Elizabeth R. Webb, Kate Yazdany, Jinoos Kim, Alfred H.J. |
author_facet | Conway, Richard Konig, Maximilian F. Graef, Elizabeth R. Webb, Kate Yazdany, Jinoos Kim, Alfred H.J. |
author_sort | Conway, Richard |
collection | PubMed |
description | Patients with inflammatory arthritis represent a possible high-risk group to COVID-19 due to their immunosuppressive regimen designed to maintain low disease activity. Thus, substantial effort has been put forth to understand the impact of COVID-19 on these patients. Patients with rheumatic diseases as a whole do not appear to be more susceptible to acquiring COVID-19. Furthermore, immunosuppression generally did not increase the likelihood of developing severe COVID-19, with the important exception of medium and high-dose glucocorticoid use. In addition, a small number of COVID-19 patients have developed new inflammatory arthritis; whether this represents an unmasking of previous subclinical disease or a bone fide virus-induced arthritis is unclear. Nevertheless, it appears that inflammatory arthritis patients currently on immunosuppression should continue their medication to prevent future flares and limit glucocorticoid usage. While this continues to be a rapidly evolving field, these data are reassuring to both patients with and providers treating inflammatory arthritides. |
format | Online Article Text |
id | pubmed-7897406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78974062021-02-22 Inflammatory arthritis in patients with COVID-19 Conway, Richard Konig, Maximilian F. Graef, Elizabeth R. Webb, Kate Yazdany, Jinoos Kim, Alfred H.J. Transl Res Review Article Patients with inflammatory arthritis represent a possible high-risk group to COVID-19 due to their immunosuppressive regimen designed to maintain low disease activity. Thus, substantial effort has been put forth to understand the impact of COVID-19 on these patients. Patients with rheumatic diseases as a whole do not appear to be more susceptible to acquiring COVID-19. Furthermore, immunosuppression generally did not increase the likelihood of developing severe COVID-19, with the important exception of medium and high-dose glucocorticoid use. In addition, a small number of COVID-19 patients have developed new inflammatory arthritis; whether this represents an unmasking of previous subclinical disease or a bone fide virus-induced arthritis is unclear. Nevertheless, it appears that inflammatory arthritis patients currently on immunosuppression should continue their medication to prevent future flares and limit glucocorticoid usage. While this continues to be a rapidly evolving field, these data are reassuring to both patients with and providers treating inflammatory arthritides. Elsevier Inc. 2021-06 2021-02-21 /pmc/articles/PMC7897406/ /pubmed/33626415 http://dx.doi.org/10.1016/j.trsl.2021.02.010 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Article Conway, Richard Konig, Maximilian F. Graef, Elizabeth R. Webb, Kate Yazdany, Jinoos Kim, Alfred H.J. Inflammatory arthritis in patients with COVID-19 |
title | Inflammatory arthritis in patients with COVID-19 |
title_full | Inflammatory arthritis in patients with COVID-19 |
title_fullStr | Inflammatory arthritis in patients with COVID-19 |
title_full_unstemmed | Inflammatory arthritis in patients with COVID-19 |
title_short | Inflammatory arthritis in patients with COVID-19 |
title_sort | inflammatory arthritis in patients with covid-19 |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897406/ https://www.ncbi.nlm.nih.gov/pubmed/33626415 http://dx.doi.org/10.1016/j.trsl.2021.02.010 |
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