Hydrogen–deuterium exchange reveals a dynamic DNA-binding map of replication protein A

Replication protein A (RPA) binds to single-stranded DNA (ssDNA) and interacts with over three dozen enzymes and serves as a recruitment hub to coordinate most DNA metabolic processes. RPA binds ssDNA utilizing multiple oligosaccharide/oligonucleotide binding domains and based on their individual DN...

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Detalles Bibliográficos
Autores principales: Ahmad, Faiz, Patterson, Angela, Deveryshetty, Jaigeeth, Mattice, Jenna R, Pokhrel, Nilisha, Bothner, Brian, Antony, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897470/
https://www.ncbi.nlm.nih.gov/pubmed/33444457
http://dx.doi.org/10.1093/nar/gkaa1288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897470/
https://www.ncbi.nlm.nih.gov/pubmed/33444457
http://dx.doi.org/10.1093/nar/gkaa1288

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