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Micro-homology intermediates: RecA’s transient sampling revealed at the single molecule level

Recombinase A (RecA) is central to homologous recombination. However, despite significant advances, the mechanism with which RecA is able to orchestrate a search for homology remains elusive. DNA nanostructure-augmented high-speed AFM offers the spatial and temporal resolutions required to study the...

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Detalles Bibliográficos
Autores principales: Lee, Andrew J, Endo, Masayuki, Hobbs, Jamie K, Davies, A Giles, Wälti, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897476/
https://www.ncbi.nlm.nih.gov/pubmed/33476368
http://dx.doi.org/10.1093/nar/gkaa1258