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Atomic resolution of short-range sliding dynamics of thymine DNA glycosylase along DNA minor-groove for lesion recognition

Thymine DNA glycosylase (TDG), as a repair enzyme, plays essential roles in maintaining the genome integrity by correcting several mismatched/damaged nucleobases. TDG acquires an efficient strategy to search for the lesions among a vast number of cognate base pairs. Currently, atomic-level details o...

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Detalles Bibliográficos
Autores principales:	Tian, Jiaqi, Wang, Lingyan, Da, Lin-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897493/ https://www.ncbi.nlm.nih.gov/pubmed/33469643 http://dx.doi.org/10.1093/nar/gkaa1252

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