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UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles
Recent advances in single-cell open-chromatin and transcriptome profiling have created a challenge of exploring novel applications with a meaningful transformation of read-counts, which often have high variability in noise and drop-out among cells. Here, we introduce UniPath, for representing single...
Autores principales: | Chawla, Smriti, Samydurai, Sudhagar, Kong, Say Li, Wu, Zhengwei, Wang, Zhenxun, TAM, Wai Leong, Sengupta, Debarka, Kumar, Vibhor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897496/ https://www.ncbi.nlm.nih.gov/pubmed/33275158 http://dx.doi.org/10.1093/nar/gkaa1138 |
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