UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles

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Recent advances in single-cell open-chromatin and transcriptome profiling have created a challenge of exploring novel applications with a meaningful transformation of read-counts, which often have high variability in noise and drop-out among cells. Here, we introduce UniPath, for representing single...

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Detalles Bibliográficos
Autores principales: Chawla, Smriti, Samydurai, Sudhagar, Kong, Say Li, Wu, Zhengwei, Wang, Zhenxun, TAM, Wai Leong, Sengupta, Debarka, Kumar, Vibhor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897496/
https://www.ncbi.nlm.nih.gov/pubmed/33275158
http://dx.doi.org/10.1093/nar/gkaa1138
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