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Ligand-dependent tRNA processing by a rationally designed RNase P riboswitch

We describe a synthetic riboswitch element that implements a regulatory principle which directly addresses an essential tRNA maturation step. Constructed using a rational in silico design approach, this riboswitch regulates RNase P-catalyzed tRNA 5′-processing by either sequestering or exposing the...

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Detalles Bibliográficos
Autores principales:	Ender, Anna, Etzel, Maja, Hammer, Stefan, Findeiß, Sven, Stadler, Peter, Mörl, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897497/ https://www.ncbi.nlm.nih.gov/pubmed/33469651 http://dx.doi.org/10.1093/nar/gkaa1282

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