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To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq
Chromatin immunoprecipitation (IP) followed by sequencing (ChIP-seq) is the gold standard to detect transcription-factor (TF) binding sites in the genome. Its success depends on appropriate controls removing systematic biases. The predominantly used controls, i.e. DNA input, correct for uneven sonic...
Autores principales: | Xu, Jinrui, Kudron, Michelle M, Victorsen, Alec, Gao, Jiahao, Ammouri, Haneen N, Navarro, Fabio C P, Gevirtzman, Louis, Waterston, Robert H, White, Kevin P, Reinke, Valerie, Gerstein, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897498/ https://www.ncbi.nlm.nih.gov/pubmed/33347581 http://dx.doi.org/10.1093/nar/gkaa1155 |
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