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Multiprotein E. coli SSB–ssDNA complex shows both stable binding and rapid dissociation due to interprotein interactions

Escherichia coli SSB (EcSSB) is a model single-stranded DNA (ssDNA) binding protein critical in genome maintenance. EcSSB forms homotetramers that wrap ssDNA in multiple conformations to facilitate DNA replication and repair. Here we measure the binding and wrapping of many EcSSB proteins to a singl...

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Detalles Bibliográficos
Autores principales: Naufer, M Nabuan, Morse, Michael, Möller, Guðfríður Björg, McIsaac, James, Rouzina, Ioulia, Beuning, Penny J, Williams, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897507/
https://www.ncbi.nlm.nih.gov/pubmed/33434279
http://dx.doi.org/10.1093/nar/gkaa1267